@biowc/pathwaygraph

biowc-pathwaygraph

biowc-pathwaygraph is a WebComponent for interactive visualization of signaling pathway diagrams. In addition to rendering the genes, proteins and compounds within a pathway, PTM and expression data can be projected onto the diagram.

Our storybook contains an overview of the features of biowc-pathwaygraph. Here's how to run it:

• Clone this repository
• Install the dependencies: npm install
• Start Storybook: npm run storybook

This webcomponent follows the open-wc recommendation.

Installation

npm i biowc-pathwaygraph

Usage

Please check demo/index.html for a minimal working example.

Linting and formatting

To scan the project for linting and formatting errors, run

npm run lint

To automatically fix linting and formatting errors, run

npm run format

Testing with Web Test Runner

To execute a single test run:

npm run test

To run the tests in interactive watch mode run:

npm run test:watch

Tooling configs

For most of the tools, the configuration is in the package.json to reduce the amount of files in your project.

If you customize the configuration a lot, you can consider moving them to individual files.

Local Demo with web-dev-server

npm start

To run a local development server that serves the basic demo located in demo/index.html

Reference

If biowc-pathwaygraph is useful for your research, please cite the following publication:

PTMNavigator: Interactive Visualization of Differentially Regulated Post-Translational Modifications in Cellular Signaling Pathways
Julian Müller, Florian P. Bayer, Mathias Wilhelm, Bernhard Kuster, Matthew The
Nature Communications 16:510 (2025); doi: https://doi.org/10.1038/s41467-024-55533-y