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deciphon

Individually annotate long, error-prone nucleotide sequences into proteins

1.0.13
PyPI
Maintainers
1

Welcome to deciphon šŸ‘‹

Individually annotate long, error-prone nucleotide sequences into proteins

šŸ  Homepage

āš”ļø Requirements

  • Python >= 3.11
  • Pip
  • Homebrew on MacOS (recommended)
  • Pipx (or uvx) for Python application management (recommended)

MacOS

Install Python and Pipx:

brew update && brew install python pipx

Ensure that your PATH environment variable is all set:

pipx ensurepath

šŸ’” You might need to close your terminal and reopen it for the changes to take effect.

Ubuntu (and Debian-based distros)

Install Python:

sudo apt update && \
    sudo apt install python3 python3-pip python3-venv --yes && \
    python3 -m pip install --user pipx

Ensure that your PATH environment variable is all set:

python3 -m pipx ensurepath

šŸ’” You might need to close your terminal and reopen it for the changes to take effect.

Install

pipx install deciphon

Usage

 Usage: deciphon [OPTIONS] COMMAND [ARGS]...

╭─ Options ────────────────────────────────────────────────────────────────────╮
│ --version          Show version.                                             │
│ --help             Show this message and exit.                               │
╰──────────────────────────────────────────────────────────────────────────────╯
╭─ Commands ───────────────────────────────────────────────────────────────────╮
│ press    Make protein database.                                              │
│ scan     Scan nucleotide sequence against protein database.                  │
│ see      Display scan results.                                               │
│ worker   Launch worker.                                                      │
╰──────────────────────────────────────────────────────────────────────────────╯

Example

Download the minifam.hmm protein database:

curl -O https://raw.githubusercontent.com/EBI-Metagenomics/deciphon/main/cli/tests/files/minifam.hmm

Download the consensus.fna file of sequences:

curl -O https://raw.githubusercontent.com/EBI-Metagenomics/deciphon/main/cli/tests/files/sequences.fna

Press it (using The Standard Code):

deciphon press minifam.hmm 1

Scan it:

deciphon scan minifam.hmm sequences.fna

Show it:

deciphon see sequences.dcs

šŸ‘¤ Author

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