The ABDesign API provides functions and data structures for dealing with Immunoglobulin sequences. It contains computational methods to 'humanize' an antibody by CDR-grafting.
Note: A local installation of ANARCI is needed for this tool. You can downlod ANARCI here.
Core data structure. All params are set on initialization, either by using create_annotation(), or manually.
seq required
chain_type
iso_type
species
annotation
regions
export_to_json()
To 'humanize' a queried sequence, a human template sequence must be provided in form of an IgObject, too. It is also possible to indicate the wanted annotation types for the hybrid IgObject. By default, all annotation systems provided by this package are applied.
FAQs
Antibody humanization framework
We found that abdesign demonstrated a healthy version release cadence and project activity because the last version was released less than a year ago. It has 1 open source maintainer collaborating on the project.
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